About the lab

Who We Are

The Bethony Laboratory, based in the Department of Microbiology, Immunology and Tropical Medicine at the George Washington University School of Medicine and Health Sciences, focuses on pre-clinical and clinical support of vaccines and translational research.

What We Do

Vaccine Projects

For more than a decade, the Bethony Lab has supported multiple vaccine projects. Some of lab’s work includes:

  • Immunology and serology assays (rodent and human) to support and evaluate pre-clinical testing, including potency assessment, and clinical (phase 1) trials.
  • Active membership of the Sabin Product Development Partnership (PDP) and the novel, low-cost, effective HOOKworm VACcine to Control Human Hookworm Infection in endemic countries (HOOKVAC) program.
  • Partnership with other vaccine development programs and area partners in their research.

Our involvement in translational medicine includes:

  • Biobanking
  • Epidemiology
  • Cohort surveys
  • Biomarker development includes:
    • Develop new methodologies and approaches to circulating microRNA (miRNA) biomarkers for Nasopharyngeal Carcinoma (NPC) and also Opisthorchis viverrini (OV) induced intrahepatic cholangiocarcinoma (ICC).
    • Use parallel proteomic approaches with our partners in Thailand and Australia to identify protein biomarkers.
    • Subsequent validation of these miRNAs or proteins for rapid and non-invasive diagnosis/prognosis of these diseases and other tumor based cancers.